Drug Information

Drug General Information
Drug ID
D0N5SS
Former ID
DCL000453
Drug Name
AZD1175
Indication Hypertension; Diabetes; Obesity [ICD9: 250, 278, 401; ICD10:E08-E13, E66, I10-I16] Discontinued in Phase 1 [548277]
Company
AstraZeneca
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Antagonist [550288]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 548277Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024090)
Ref 550288Clinical pipeline report, company report or official report of AstraZeneca (2009).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.