Drug Information

Drug General Information
Drug ID
D0N4RO
Former ID
DIB019308
Drug Name
compound 1b
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529216]
Formula
C24H23NO3S
InChI
InChI=1S/C24H23NO3S/c26-23(22(29)16-17-7-3-1-4-8-17)25-21(24(27)28)15-18-11-13-20(14-12-18)19-9-5-2-6-10-19/h1-14,21-22,29H,15-16H2,(H,25,26)(H,27,28)/t21-,22+/m0/s1
InChIKey
BNECOBGISSOLPT-FCHUYYIVSA-N
PubChem Compound ID
44377139
PubChem Substance ID
103416944, 104128295, 252166827
Target and Pathway
Target(s) Neutral endopeptidase Target Info Inhibitor [529216]
Carboxypeptidase A1 (pancreatic) Target Info Inhibitor [529216]
KEGG Pathway Renin-angiotensin system
Hematopoietic cell lineage
Protein digestion and absorption
Alzheimer's disease
NetPath Pathway EGFR1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways Metabolism of Angiotensinogen to Angiotensins
Primary Focal Segmental Glomerulosclerosis FSGS
Alzheimers Disease
References
Ref 529216Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett. 2008 Jan 15;18(2):732-7. Epub 2007 Nov 19.
Ref 529216Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett. 2008 Jan 15;18(2):732-7. Epub 2007 Nov 19.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.