Drug Information

Drug General Information
Drug ID
D0N2KP
Former ID
DNC004032
Drug Name
2,5-Bis-(3-cyclopentyloxy-4-methoxy-phenyl)-furan
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525447]
Formula
C28H32O5
Canonical SMILES
COC1=C(C=C(C=C1)C2=CC=C(O2)C3=CC(=C(C=C3)OC)OC4CCCC4)OC<br />5CCCC5
InChI
1S/C28H32O5/c1-29-25-13-11-19(17-27(25)31-21-7-3-4-8-21)23-15-16-24(33-23)20-12-14-26(30-2)28(18-20)32-22-9-5-6-10-22/h11-18,21-22H,3-10H2,1-2H3
InChIKey
VJENKFARFHFXFG-UHFFFAOYSA-N
PubChem Compound ID
44339586
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [525447]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 525447Bioorg Med Chem Lett. 1999 Feb 8;9(3):323-6.Substituted furans as inhibitors of the PDE4 enzyme.
Ref 525447Bioorg Med Chem Lett. 1999 Feb 8;9(3):323-6.Substituted furans as inhibitors of the PDE4 enzyme.

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