Drug Information

Drug General Information
Drug ID
D0MX1T
Former ID
DNC012252
Drug Name
Methyl-(1,2,3,4-tetrahydro-naphthalen-1-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533451]
Formula
C11H15N
Canonical SMILES
CNC1CCCC2=CC=CC=C12
InChI
1S/C11H15N/c1-12-11-8-4-6-9-5-2-3-7-10(9)11/h2-3,5,7,11-12H,4,6,8H2,1H3
InChIKey
JQEUPNKUYMHYPW-UHFFFAOYSA-N
PubChem Compound ID
46475
Target and Pathway
Target(s) Amine oxidase [flavin-containing] B Target Info Inhibitor [533451]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Dopamine degradation
Putrescine degradation III
Noradrenaline and adrenaline degradation
KEGG Pathway Glycine, serine and threonine metabolism
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Drug metabolism - cytochrome P450
Metabolic pathways
Serotonergic synapse
Dopaminergic synapse
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine degredation
Dopamine receptor mediated signaling pathway
Pathway Interaction Database Alpha-synuclein signaling
WikiPathways Tryptophan metabolism
Dopamine metabolism
Phase 1 - Functionalization of compounds
References
Ref 533451J Med Chem. 1988 Aug;31(8):1558-66.Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site.
Ref 533451J Med Chem. 1988 Aug;31(8):1558-66.Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site.

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