Drug Information

Drug General Information
Drug ID
D0MU1V
Former ID
DIB018773
Drug Name
AG-26
Synonyms
AG26; AG 26
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541422]
Formula
C16H17ClN2O2
InChI
InChI=1S/C16H17ClN2O2/c1-21-15-8-2-12(3-9-15)10-11-18-16(20)19-14-6-4-13(17)5-7-14/h2-9H,10-11H2,1H3,(H2,18,19,20)
InChIKey
OVFMMJNKICPJJH-UHFFFAOYSA-N
PubChem Compound ID
727787
PubChem Substance ID
944085, 6524180, 9306170, 35404380, 48469180, 53449301, 108395122, 109862241, 123098864, 124532248, 178102888
Target and Pathway
Target(s) FMLP-related receptor I Target Info Agonist [530510]
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 541422(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6268).
Ref 530510Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition. Mol Pharmacol. 2010 Feb;77(2):159-70.

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