Drug Information

Drug General Information
Drug ID
D0MS3V
Former ID
DNC014197
Drug Name
2-(Biphenyl-3-ylthio)-N,N-dimethylethanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530699]
Formula
C16H19NS
Canonical SMILES
CN(C)CCSC1=CC=CC(=C1)C2=CC=CC=C2
InChI
1S/C16H19NS/c1-17(2)11-12-18-16-10-6-9-15(13-16)14-7-4-3-5-8-14/h3-10,13H,11-12H2,1-2H3
InChIKey
NDJKJLMJAGRKRK-UHFFFAOYSA-N
PubChem Compound ID
46233485
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [530699]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 530699Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.
Ref 530699Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.

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