Drug Information

Drug General Information
Drug ID
D0MC9C
Former ID
DIB019263
Drug Name
compound 16
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531216]
Formula
C18H33N3O5
InChI
InChI=1S/C18H33N3O5/c1-18(2,3)26-17(24)20-14(11-5-4-6-12-15(22)21-25)16(23)19-13-9-7-8-10-13/h13-14,25H,4-12H2,1-3H3,(H,19,23)(H,20,24)(H,21,22)/t14-/m0/s1
InChIKey
YKINZQJOQFMNPU-AWEZNQCLSA-N
PubChem Compound ID
50908800
PubChem Substance ID
111327577, 123089146, 123110221, 178103636
Target and Pathway
Target(s) Histone deacetylase 6 Target Info Inhibitor [531216]
KEGG Pathway Alcoholism
Viral carcinogenesis
Pathway Interaction Database Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class I
Reactome NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Assembly of the primary cilium
WikiPathways Ectoderm Differentiation
Neural Crest Differentiation
Cell Cycle
References
Ref 531216Bioorg Med Chem Lett. 2010 Dec 1;20(23):7067-70. Epub 2010 Oct 12.Inhibitors selective for HDAC6 in enzymes and cells.
Ref 531216Bioorg Med Chem Lett. 2010 Dec 1;20(23):7067-70. Epub 2010 Oct 12.Inhibitors selective for HDAC6 in enzymes and cells.

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