Drug Information

Drug General Information
Drug ID
D0M8PM
Former ID
DIB003356
Drug Name
IRX-4
Synonyms
IRX-2 + tumor-specific antigen (cancer), IRx Therapeutics
Indication Prostate cancer [ICD9: 185; ICD10:C61] Preclinical [548530]
Company
IRX Therapeutics Inc
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info Immunomodulator (Immunostimulant) [532510]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 548530Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026363)
Ref 532510Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development. Dev Dyn. 2014 Mar;243(3):381-92.

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