Drug Information

Drug General Information
Drug ID
D0M7TW
Former ID
DIB012289
Drug Name
PF-3900422
Synonyms
PF-03900422; Histamine H3 receptor antagonist (central nervous system disease), Pfizer
Indication Central nervous system disease [ICD10:G00-G99] Investigative [543673]
Company
Pfizer Inc
Canonical SMILES
C(=O)(c1cc(ccc1)c1cc2c(cc1)CC(CC2)N1CCCC1)N(C)CC
Target and Pathway
Target(s) Histamine H3 receptor Target Info Antagonist [543673]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 543673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).
Ref 543673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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