TTD | Drug: D0M2WZ

Drug General Information
Drug ID	D0M2WZ
Former ID	DIB002039
Drug Name	NS-2710
Synonyms	ME-3127
Drug Type	Small molecular drug
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Phase 2	[531250]
Company	NeuroSearch A/S
Formula	C22H20N4O
Canonical SMILES	n1(cnc2c1ccc(c2)/C(=N/OCC)/C)c1cc(c2cnccc2)ccc1
PubChem Compound ID	9863520
Target and Pathway
Target(s)	Gamma-aminobutyric-acid receptor alpha-3 subunit	Target Info	Modulator	[531250]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WikiPathways	Iron uptake and transport
References
Ref 531250	GABAA receptor subtype-selective modulators. I. alpha2/alpha3-selective agonists as non-sedating anxiolytics. Curr Top Med Chem. 2011;11(9):1176-202.
Ref 531250	GABAA receptor subtype-selective modulators. I. alpha2/alpha3-selective agonists as non-sedating anxiolytics. Curr Top Med Chem. 2011;11(9):1176-202.

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Drug Information