Drug Information

Drug General Information
Drug ID
D0M0UJ
Former ID
DIB002639
Drug Name
GS-9148
Synonyms
GS-9131; Nucleoside reverse transcriptase inhibitor (HIV infection), Gilead Sciences; Mono-amidate prodrug of GS-9148 (HIV infection), Gilead
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Terminated [547439]
Company
Gilead Sciences Inc
Formula
C10H11FN5O5P
Canonical SMILES
OP(=O)(O)CO[C@H]1O[C@@H](n2c3c(nc2)c(ncn3)N)C(=C1)F
PubChem Compound ID
15958718
Target and Pathway
Target(s) HIV reverse transcriptase Target Info Inhibitor [529800]
References
Ref 547439Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016343)
Ref 529800Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation. Antimicrob Agents Chemother. 2009 Jan;53(1):150-6.

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