Drug Information

Drug General Information
Drug ID
D0LL4C
Former ID
DNC001448
Drug Name
TIP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534987]
Formula
O-2
Canonical SMILES
[O-2]
InChI
1S/O/q-2
InChIKey
AHKZTVQIVOEVFO-UHFFFAOYSA-N
CAS Number
CAS 88149-94-4
PubChem Compound ID
190217
PubChem Substance ID
7887223, 7890784, 10261150, 11534160, 14842769, 33511569, 57396438, 75980933, 103843696, 113447953, 117385022, 134340630, 135169214, 142459773, 162801284
Target and Pathway
Target(s) Delta-type opioid receptor Target Info Antagonist [534987]
KEGG Pathway cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Opioid proenkephalin pathway
Opioid proopiomelanocortin pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 534987The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25.
Ref 534987The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists. Biopolymers. 1999;51(6):411-25.

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