Drug Information

Drug General Information
Drug ID
D0L6VH
Former ID
DIB005930
Drug Name
BF-389
Drug Type
Small molecular drug
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Phase 1 [526850]
Company
Biofor Inc
Formula
C20H29NO3
Canonical SMILES
C1(=O)/C(=C/c2cc(c(c(C(C)(C)C)c2)O)C(C)(C)C)/CCON1C
CAS Number
CAS 127245-22-1
PubChem Compound ID
6439259
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Modulator [526850]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 526850Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8.
Ref 526850Antiarthritic profile of BF-389--a novel anti-inflammatory agent with low ulcerogenic liability. Agents Actions. 1992 Sep;37(1-2):90-8.

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