Drug Information

Drug General Information
Drug ID
D0KY9B
Former ID
DNC002965
Drug Name
5-Chloryl-2,4,6-Quinazolinetriamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C8H8ClN5
Canonical SMILES
C1=CC2=C(C(=C1N)Cl)C(=NC(=N2)N)N
InChI
1S/C8H8ClN5/c9-6-3(10)1-2-4-5(6)7(11)14-8(12)13-4/h1-2H,10H2,(H4,11,12,13,14)
InChIKey
JZWXVYNQIJJTKF-UHFFFAOYSA-N
PubChem Compound ID
152217
PubChem Substance ID
826353, 7805119, 7886652, 10251447, 46228661, 50554352, 91574545, 103165079, 104433097, 121276649, 125675148, 128351641, 135258710, 137030683, 162803478, 163353686, 216249364, 225000880, 227804240, 249529308
Target and Pathway
Target(s) Dihydrofolate reductase Target Info Inhibitor [551393]
PathWhiz Pathway Folate Metabolism
Pterine Biosynthesis
Reactome E2F mediated regulation of DNA replication
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Metabolism of folate and pterines
G1/S-Specific Transcription
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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