TTD | Drug: D0KX3H

Drug General Information
Drug ID	D0KX3H
Former ID	DNC001178
Drug Name	Pyrrolopyrimidine
Indication	Discovery agent		Investigative	[536141]
Target and Pathway
Target(s)	Multidrug resistance-associated protein 1	Target Info	Inhibitor	[536141]
KEGG Pathway	ABC transporters
	Sphingolipid signaling pathway
	Vitamin digestion and absorption
	MicroRNAs in cancer
NetPath Pathway	IL6 Signaling Pathway
Pathway Interaction Database	S1P1 pathway
Pathway Interaction Database	Sphingosine 1-phosphate (S1P) pathway
Reactome	Cobalamin (Cbl, vitamin B12) transport and metabolism
Reactome	ABC-family proteins mediated transport
WikiPathways	Arachidonic acid metabolism
	Irinotecan Pathway
	Metabolism of water-soluble vitamins and cofactors
References
Ref 536141	Topological model for the prediction of MRP1 inhibitory activity of pyrrolopyrimidines and templates derived from pyrrolopyrimidine. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4967-72.
Ref 536141	Topological model for the prediction of MRP1 inhibitory activity of pyrrolopyrimidines and templates derived from pyrrolopyrimidine. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4967-72.

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Drug Information