Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K9ZU
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| Former ID |
DIB006843
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| Drug Name |
CD45RB
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| Synonyms |
Abeta amyloid agonist (peptide, glioma); Abeta amyloid agonist (peptide, glioma), Lee Moffitt Cancer Center
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| Indication | Glioma [ICD9: 191; ICD10:C71] | Investigative | [543619] | ||
| Company |
H Lee Moffitt Cancer Center and Research Institute
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| Canonical SMILES |
N([C@H](C(=O)O)Cc1ccccc1)C(=O)[C@@H](NC(=O)[C@H](C(C)C)<br />NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(<br />=O)[C@@H](NC(=O)[C@@H](N)C(C)C)Cc1c[nH]cn1)Cc1c[nH]cn1)<br />CCC(=O)N)CCCCN)CC(C)C)Cc1ccccc1
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| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Agonist | [543619] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
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