Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K9PS
|
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| Former ID |
DIB015095
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| Drug Name |
CHF-5480
|
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| Synonyms |
CHF-5480; PDE 4 inhibitors (COPD/asthma); PDE 4 inhibitors (COPD/asthma), Chiesi
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| Indication | Asthma; Chronic obstructive pulmonary disease [ICD9: 490-492, 493, 494-496; ICD10:J40-J44, J47, J45] | Investigative | [543404] | ||
| Company |
Chiesi Farmaceutici SpA
|
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| Canonical SMILES |
c1(c(ccc(c1)/C(=C/c1c(cncc1Cl)Cl)/OC(=O)[C@H](c1ccc(cc1<br />)CC(C)C)C)OC)OC
|
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| Target and Pathway | |||||
| Target(s) | CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [543404] | |
| Type IV phosphodiesterase | Target Info | Inhibitor | [543406] | ||
| CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [543405] | ||
| NetPath Pathway | IL5 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| PathWhiz Pathway | Purine Metabolism | ||||
| References | |||||
| Ref 543404 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1300). | ||||
| Ref 543405 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1301). | ||||
| Ref 543406 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1303). | ||||
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