Drug Information

Drug General Information
Drug ID
D0K0KP
Former ID
DIB008391
Drug Name
GE-68
Drug Type
Small molecular drug
Indication Heart arrhythmia [ICD10:I47-I49] Terminated [544938]
Company
University of Vienna
Formula
C21H25NO2
Canonical SMILES
CCCNCC(C1=C(C2=CC=CC=C2O1)CCC3=CC=CC=C3)O
InChI
1S/C21H25NO2/c1-2-14-22-15-19(23)21-18(13-12-16-8-4-3-5-9-16)17-10-6-7-11-20(17)24-21/h3-11,19,22-23H,2,12-15H2,1H3
InChIKey
XPEXCFSBFPOSQR-UHFFFAOYSA-N
CAS Number
CAS 157493-95-3
PubChem Compound ID
133044
PubChem Substance ID
10243281, 14777149, 29311051, 74721689, 103305893, 104378864, 126437559, 129721184, 135088653, 235111141
Target and Pathway
Target(s) Sodium channel Target Info Modulator [534330]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 544938Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001596)
Ref 534330Electrophysiological properties of the propafenone-analogue GE 68 (1-[3-(phenylethyl)-2-benzofuryl]-2-(propylamino)-ethanol) in isolated preparations and ventricular myocytes of guinea-pig hearts. Naunyn Schmiedebergs Arch Pharmacol. 1997 Feb;355(2):230-8.

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