Drug Information

Drug General Information
Drug ID
D0J7MQ
Former ID
DIB000865
Drug Name
MKC-1106-MT
Synonyms
Melanoma vaccine (MART-1/tyrosinase), Mannkind
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 2 [522880]
Company
Colby pharmaceuticals
Target and Pathway
Target(s) MART-1 melanoma antigen Target Info Modulator [1572591]
Tyrosine oxidase Target Info Modulator [1572591]
BioCyc Pathway (S)-reticuline biosynthesis
Eumelanin biosynthesis
L-dopachrome biosynthesis
KEGG Pathway Tyrosine metabolism
Riboflavin metabolism
Metabolic pathways
Melanogenesis
PathWhiz Pathway Riboflavin Metabolism
Tyrosine Metabolism
WikiPathways Dopamine metabolism
References
Ref 522880ClinicalTrials.gov (NCT01026051) Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma. U.S. National Institutes of Health.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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