Drug Information

Drug General Information
Drug ID
D0J7MD
Former ID
DNC012707
Drug Name
(6-Methoxy-2-oxo-2H-quinolin-1-yl)-acetic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533420]
Formula
C12H11NO4
Canonical SMILES
COC1=CC2=C(C=C1)N(C(=O)C=C2)CC(=O)O
InChI
1S/C12H11NO4/c1-17-9-3-4-10-8(6-9)2-5-11(14)13(10)7-12(15)16/h2-6H,7H2,1H3,(H,15,16)
InChIKey
CHNXZDVEGNIZLG-UHFFFAOYSA-N
PubChem Compound ID
13683078
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [533420]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 533420J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.
Ref 533420J Med Chem. 1986 Oct;29(10):2024-8.Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives.

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