Drug Information

Drug General Information
Drug ID
D0J7AI
Former ID
DIB000154
Drug Name
BN-80245
Synonyms
DU-1441; DU-1442
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Terminated [546946]
Company
Institut Henri Beaufour
Formula
C21H18N2O4
Canonical SMILES
n12c(c3c(C2)cc2c(n3)cccc2)cc2c(c1=O)COC(=O)CC2(O)CC
PubChem Compound ID
9863779
Target and Pathway
Target(s) Toposisomerase-1 Target Info Inhibitor [551651]
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway DNA replication
Pathway Interaction Database Caspase Cascade in Apoptosis
WikiPathways Integrated Pancreatic Cancer Pathway
References
Ref 546946Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011416)
Ref 551651BN 80245: An E-ring modified camptothecin with potent antiproliferative and topoisomerase I inhibitory activities. Bioorganic & Medicinal Chemistry Letters Volume 7, Issue 17, 9 September 1997, Pages2235-2238.

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