Drug Information

Drug General Information
Drug ID
D0J6RQ
Former ID
DNC008724
Drug Name
1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529286]
Formula
C17H14O3
Canonical SMILES
C1=CC(=CC=C1C=CC(=O)C=CC2=CC=C(C=C2)O)O
InChI
1S/C17H14O3/c18-15-7-1-13(2-8-15)5-11-17(20)12-6-14-3-9-16(19)10-4-14/h1-12,18-19H/b11-5+,12-6+
InChIKey
FTEGUKWEUQPKIS-YDWXAUTNSA-N
PubChem Compound ID
6437306
Target and Pathway
Target(s) Cytochrome P450 2D6 Target Info Inhibitor [529286]
KEGG Pathway Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Serotonergic synapse
Reactome Xenobiotics
WikiPathways Metapathway biotransformation
Tamoxifen metabolism
Oxidation by Cytochrome P450
Vitamin D Receptor Pathway
Aripiprazole Metabolic Pathway
Fatty Acid Omega Oxidation
Codeine and Morphine Metabolism
References
Ref 529286Eur J Med Chem. 2008 Aug;43(8):1621-31. Epub 2007 Nov 17.Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues.
Ref 529286Eur J Med Chem. 2008 Aug;43(8):1621-31. Epub 2007 Nov 17.Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues.

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