TTD | Drug: D0J1HP

Drug General Information
Drug ID	D0J1HP
Former ID	DNC004124
Drug Name	(R)-2-(Benzylamino-methyl)-chroman-7-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526840]
Formula	C17H19NO2
Canonical SMILES	C1CC2=C(C=C(C=C2)O)OC1CNCC3=CC=CC=C3
InChI	1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1
InChIKey	DWUAAOIZQFTYQP-MRXNPFEDSA-N
PubChem Compound ID	10378389
Target and Pathway
Target(s)	D(3) dopamine receptor	Target Info	Inhibitor	[526840]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Dopaminergic synapse
Reactome	Dopamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
	GPCRs, Other
References
Ref 526840	J Med Chem. 2003 Oct 9;46(21):4377-92.Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Ref 526840	J Med Chem. 2003 Oct 9;46(21):4377-92.Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.

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Drug Information