Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0IZ1D
|
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| Former ID |
DIB009881
|
||||
| Drug Name |
Brofaromine
|
||||
| Synonyms |
Brofaremine; Consonar; Consonev; Brofaromine hydrochloride; CGP-11305A
|
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| Drug Type |
Small molecular drug
|
||||
| Indication | Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] | Discontinued in Phase 2 | [544708] | ||
| Company |
Novartis AG
|
||||
| Formula |
C14H16BrNO2
|
||||
| Canonical SMILES |
o1c(cc2c1c(cc(c2)OC)Br)C1CCNCC1
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] A | Target Info | Modulator | [533333] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| References | |||||
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