Drug Information

Drug General Information
Drug ID
D0I8GD
Former ID
DIB020419
Drug Name
MRS1186
Synonyms
MRS-1186
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467929]
Formula
C16H12ClN5O2
InChI
InChI=1S/C16H12ClN5O2/c1-2-13(23)19-16-18-11-6-5-9(17)8-10(11)15-20-14(21-22(15)16)12-4-3-7-24-12/h3-8H,2H2,1H3,(H,18,19,23)
InChIKey
SPZIDRYLSXDAEF-UHFFFAOYSA-N
PubChem Compound ID
10065929
PubChem Substance ID
15050973, 22483418, 44182946, 75624221, 103310469, 103950590, 129272011, 135650646, 227851335
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Antagonist [534241]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 467929(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 469).
Ref 534241Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype. J Med Chem. 1996 Oct 11;39(21):4142-8.

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