Drug Information

Drug General Information
Drug ID
D0I6KF
Former ID
DNC013045
Drug Name
(S)-(-)-(4,5,6-trimethoxyindan-1-yl)methanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528294]
Formula
C13H19NO3
Canonical SMILES
COC1=C(C(=C2CCC(C2=C1)CN)OC)OC
InChI
1S/C13H19NO3/c1-15-11-6-10-8(7-14)4-5-9(10)12(16-2)13(11)17-3/h6,8H,4-5,7,14H2,1-3H3/t8-/m1/s1
InChIKey
AFTIZGHFDCOQFS-MRVPVSSYSA-N
PubChem Compound ID
11514605
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [528294]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 528294J Med Chem. 2006 Jul 13;49(14):4269-74.C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor.
Ref 528294J Med Chem. 2006 Jul 13;49(14):4269-74.C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor.

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