Drug Information

Drug General Information
Drug ID
D0I5PY
Former ID
DNC010526
Drug Name
1-(biphenyl-3-ylmethyl)-1H-1,2,4-triazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530712]
Formula
C15H13N3
Canonical SMILES
C1=CC=C(C=C1)C2=CC(=CC=C2)CN3C=NC=N3
InChI
1S/C15H13N3/c1-2-6-14(7-3-1)15-8-4-5-13(9-15)10-18-12-16-11-17-18/h1-9,11-12H,10H2
InChIKey
OZOOKYPKFWRQMO-UHFFFAOYSA-N
PubChem Compound ID
23585406
Target and Pathway
Target(s) Cytochrome P450 19 Target Info Inhibitor [530712]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Estradiol biosynthesis II
Estradiol biosynthesis I
KEGG Pathway Steroid hormone biosynthesis
Metabolic pathways
Ovarian steroidogenesis
NetPath Pathway FSH Signaling Pathway
PANTHER Pathway Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Endogenous sterols
WikiPathways Metapathway biotransformation
Tryptophan metabolism
Oxidation by Cytochrome P450
Ovarian Infertility Genes
Metabolism of steroid hormones and vitamin D
FSH signaling pathway
Integrated Breast Cancer Pathway
Phase 1 - Functionalization of compounds
References
Ref 530712J Med Chem. 2010 Mar 11;53(5):2155-70.Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
Ref 530712J Med Chem. 2010 Mar 11;53(5):2155-70.Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.

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