TTD | Drug: D0I4UU

Drug General Information
Drug ID	D0I4UU
Former ID	DIB019884
Drug Name	FUB 349
Synonyms	FUB-349; FUB349
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538774]
Formula	C13H16N2
InChI	InChI=1S/C13H16N2/c1-2-6-12(7-3-1)8-4-5-9-13-10-14-11-15-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,14,15)
InChIKey	BQTXNCXSCSNHGA-UHFFFAOYSA-N
PubChem Compound ID	9990388
PubChem Substance ID	14968926, 44041711, 56241983, 76150619, 103225547, 103964986, 134340900, 135650291
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[525918]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538774	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1259).
Ref 525918	Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain. Br J Pharmacol. 2000 Dec;131(7):1247-50.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.

Drug Information