Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0I2VK
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| Former ID |
DAP000577
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| Drug Name |
Isocarboxazid
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| Synonyms |
BMIH; Benazide; Enerzer; Isocarbonazid; Isocarbossazide; Isocarboxazida; Isocarboxazide; Isocarboxazidum; Isocarboxyzid; Maraplan; Marplan; Marplon; Isocarbossazide [DCIT]; Isocarboxazid (INN); Isocarboxazid [INN:BAN]; Isocarboxazida [INN-Spanish]; Isocarboxazide [INN-French]; Isocarboxazidum [INN-Latin]; Marplan (TN); Ro5-0831; Ro 5-0831/1; N'-Benzyl N-methyl-5-isoxazolecarboxylhydrazide-3; N'-benzyl-5-methyl-1,2-oxazole-3-carbohydrazide; 1-Benzyl-2-(5-methyl-3-isoxazolyl-carbonyl)hydrazine; 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine; 3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide; 3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide; 5-Methyl-3-isoxazolecarboxylic acid 2-benzylhydrazide; 5-methyl-N'-(phenylmethyl)isoxazole-3-carbohydrazide
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antidepressants
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| Company |
Hoffmann-La Roche pharmaceutical company
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| Formula |
C12H13N3O2
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| InChI |
InChI=1S/C12H13N3O2/c1-9-7-11(15-17-9)12(16)14-13-8-10-5-3-2-4-6-10/h2-7,13H,8H2,1H3,(H,14,16)
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| InChIKey |
XKFPYPQQHFEXRZ-UHFFFAOYSA-N
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| CAS Number |
CAS 59-63-2
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| PubChem Compound ID | |||||
| PubChem Substance ID |
442485, 4667752, 8152378, 10528879, 11112152, 11466823, 11467943, 11486605, 16885460, 17396751, 29222879, 46505330, 47365381, 48185156, 48185157, 48334685, 48416130, 49699170, 49987628, 50100378, 50591995, 56463226, 57321980, 58106974, 85789365, 92125896, 99358097, 103771151, 103914493, 104231731, 104304439, 121363567, 124799381, 124881991, 126646731, 134337868, 134972611, 136214439, 137002954, 139640708, 144203887, 160825711, 160964579, 163092606, 163389007, 163842003, 172908333, 175267943, 175612006, 178103779
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| SuperDrug ATC ID |
N06AF01
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| SuperDrug CAS ID |
cas=000059632
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| Target and Pathway | |||||
| Target(s) | Amine oxidase [flavin-containing] A | Target Info | Inhibitor | [537841] | |
| KEGG Pathway | Glycine, serine and threonine metabolism | ||||
| Arginine and proline metabolism | |||||
| Histidine metabolism | |||||
| Tyrosine metabolism | |||||
| Phenylalanine metabolism | |||||
| Tryptophan metabolism | |||||
| Drug metabolism - cytochrome P450 | |||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Dopaminergic synapse | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Alcoholism | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| References | |||||
| Ref 538453 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 011961. | ||||
| Ref 542218 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7204). | ||||
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