Drug Information

Drug General Information
Drug ID
D0H6JC
Former ID
DNC011974
Drug Name
1,2-Dihydro-indazol-3-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529474]
Formula
C7H6N2O
Canonical SMILES
C1=CC=C2C(=C1)C(=O)NN2
InChI
1S/C7H6N2O/c10-7-5-3-1-2-4-6(5)8-9-7/h1-4H,(H2,8,9,10)
InChIKey
SWEICGMKXPNXNU-UHFFFAOYSA-N
PubChem Compound ID
81829
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [529474]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 529474J Med Chem. 1991 Mar;34(3):1028-36.Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.
Ref 529474J Med Chem. 1991 Mar;34(3):1028-36.Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.

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