TTD | Drug: D0H3YR

Drug General Information
Drug ID	D0H3YR
Former ID	DIB018399
Drug Name	[3H]robalzotan
Synonyms	[3H]NAD-299; [3H]NAD 299
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542993]
Formula	C18H23FN2O2
InChI	InChI=1S/C18H23FN2O2/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12/h7-8,11-13H,1-6,9-10H2,(H2,20,22)/t13-/m1/s1/i7T
InChIKey	MQTUXRKNJYPMCG-FZQCOGARSA-N
PubChem Compound ID	10591800
PubChem Substance ID	15620855, 22896871, 41226953, 50554012, 124960513, 135651184
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Antagonist	[534771]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 542993	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 82).
Ref 534771	Receptor binding characteristics of [3H]NAD-299, a new selective 5-HT1A receptor antagonist. Eur J Pharmacol. 1998 Nov 6;360(2-3):219-25.

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Drug Information