Drug Information

Drug General Information
Drug ID
D0H3CV
Former ID
DIB014976
Drug Name
Ro-48-8724
Indication Multidrug resistant infection [ICD10:A00-B99] Terminated [546449]
Company
F Hoffmann-La Roche Ltd
Canonical SMILES
N12C(=O)[C@H]3N(C(=O)C(F)(F)F)C[C@H]([C@@H]13)CC(=C2C(=<br />O)[O-])COC(=O)N.[Na+]
CAS Number
CAS 170581-96-1
Target and Pathway
Target(s) Beta-lactamase Target Info Modulator [534754]
References
Ref 546449Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008187)
Ref 534754Activity of a broad-spectrum cephalosporin (Ro 48-8391) alone and in combination with two novel beta-lactamase inhibitors (Ro 48-5545 and Ro 48-8724). Diagn Microbiol Infect Dis. 1998 Oct;32(2):85-94.

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