Drug Information

Drug General Information
Drug ID
D0H2NI
Former ID
DIB013658
Drug Name
YM-543
Synonyms
ASP-543; SGLT-2 inhibitor (oral, diabetes), Astellas/Kotobuki
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [521996]
Company
Kotobuki Pharmaceutical Co Ltd
Target and Pathway
Target(s) SLGT2 Target Info Modulator
Reactome Hexose transport
Na+-dependent glucose transporters
Inositol transporters
WikiPathways NRF2 pathway
Nuclear Receptors Meta-Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 521996ClinicalTrials.gov (NCT00454233) A Safety and Efficacy Study With YM543 in Type 2 Diabetes Mellitus Subjects. U.S. National Institutes of Health.

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