Drug Information

Drug General Information
Drug ID
D0H1YE
Former ID
DIB014253
Drug Name
BE-22179
Indication Leukemia [ICD9: 208.9; ICD10:C90-C95] Terminated [545707]
Company
MSD Japan
Formula
C46H48N10O12S4
Canonical SMILES
C1(=O)N(C(=C)C(=O)SCC(C(=O)NCC(=O)N(C2C(=O)N(C(=C)C(=O)<br />SCC(C(=O)NCC(=O)N(C1CSSC2)C)NC(=O)c1nc2c(cc1O)cccc2)C)C<br />)NC(=O)c1nc2c(cc1O)cccc2)C
CAS Number
CAS 147816-33-9
PubChem Compound ID
164474
Target and Pathway
Target(s) DNA topoisomerase II Target Info Modulator [533914]
References
Ref 545707Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004286)
Ref 533914A new topoisomerase II inhibitor, BE-22179, produced by a streptomycete. I. Producing strain, fermentation, isolation and biological activity. J Antibiot (Tokyo). 1994 Feb;47(2):129-35.

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