Drug Information

Drug General Information
Drug ID
D0GX8F
Former ID
DNC005127
Drug Name
BN-82002
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [527263]
Target and Pathway
Target(s) M-phase inducer phosphatase 3 Target Info Inhibitor [527263]
KEGG Pathway Cell cycle
Oocyte meiosis
Progesterone-mediated oocyte maturation
MicroRNAs in cancer
PANTHER Pathway p53 pathway
Pathway Interaction Database ATR signaling pathway
ATM pathway
PLK1 signaling events
PLK3 signaling events
Reactome Polo-like kinase mediated events
Cyclin B2 mediated events
Activation of ATR in response to replication stress
RHO GTPases activate PKNs
Cyclin A/B1 associated events during G2/M transition
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
WikiPathways Monoamine Transport
DNA Damage Response
ATM Signaling Pathway
Integrated Pancreatic Cancer Pathway
Mitotic G2-G2/M phases
Cell Cycle
Cell Cycle Checkpoints
miRNA Regulation of DNA Damage Response
References
Ref 527263Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12.Synthesis of small molecule CDC25 phosphatases inhibitors.
Ref 527263Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12.Synthesis of small molecule CDC25 phosphatases inhibitors.

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