Drug Information

Drug General Information
Drug ID
D0G6OW
Former ID
DNC004957
Drug Name
Sodium 2,3,5,6-tetrafluorobenzoate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530027]
Formula
C7HF4NaO2
Canonical SMILES
C1=C(C(=C(C(=C1F)F)C(=O)[O-])F)F.[Na+]
InChI
1S/C7H2F4O2.Na/c8-2-1-3(9)6(11)4(5(2)10)7(12)13;/h1H,(H,12,13);/q;+1/p-1
InChIKey
ZESSIGXSSUUGNU-UHFFFAOYSA-M
PubChem Compound ID
23675285
Target and Pathway
Target(s) Carbonic anhydrase II Target Info Inhibitor [530027]
KEGG Pathway Nitrogen metabolism
Proximal tubule bicarbonate reclamation
Collecting duct acid secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
NetPath Pathway IL4 Signaling Pathway
EGFR1 Signaling Pathway
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 530027Bioorg Med Chem. 2009 Apr 1;17(7):2654-7. Epub 2009 Mar 5.Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates.
Ref 530027Bioorg Med Chem. 2009 Apr 1;17(7):2654-7. Epub 2009 Mar 5.Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates.

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