Drug Information

Drug General Information
Drug ID
D0G6EO
Former ID
DIB001842
Drug Name
Hemoximer
Synonyms
PHP-CT; PHP-HT; PHP-OC; Pyridoxalated hemoglobin polyoxyethylene-CT; Pyridoxalated hemoglobin polyoxyethylene-HT; Pyridoxalated hemoglobin polyoxyethylene-OC; VTR-PHP
Indication Hypotension [ICD9: 458, 796.3; ICD10:I95] Discontinued in Phase 3 [546525]
Company
Ajinomoto Co Inc
Target and Pathway
Target(s) Hemoglobin Target Info Antagonist [550037]
KEGG Pathway African trypanosomiasis
Malaria
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Scavenging of heme from plasma
WikiPathways Binding and Uptake of Ligands by Scavenger Receptors
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
Factors involved in megakaryocyte development and platelet production
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 546525Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008774)
Ref 550037Effect of NaBH4 Concentration and Reaction Time on Physical Properties of Glutaraldehyde-Polymerized Hemoglobin. Biotechnology Progress. 05/2004; 20(3):946-52.

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