Drug Information

Drug General Information
Drug ID
D0F6VI
Former ID
DNC010691
Drug Name
N-(3-(2-hydroxy-5-methoxyphenyl)propyl)acetamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530786]
Formula
C12H17NO3
Canonical SMILES
CC(=O)NCCCC1=C(C=CC(=C1)OC)O
InChI
1S/C12H17NO3/c1-9(14)13-7-3-4-10-8-11(16-2)5-6-12(10)15/h5-6,8,15H,3-4,7H2,1-2H3,(H,13,14)
InChIKey
OMOWUWLCRNGXCM-UHFFFAOYSA-N
PubChem Compound ID
46885230
Target and Pathway
Target(s) Melatonin receptor type 1B Target Info Inhibitor [530786]
Melatonin receptor Target Info Inhibitor [530786]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainmenthsa04080:Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
GPCR downstream signaling
References
Ref 530786Bioorg Med Chem Lett. 2010 Apr 15;20(8):2582-5. Epub 2010 Feb 25.Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands.
Ref 530786Bioorg Med Chem Lett. 2010 Apr 15;20(8):2582-5. Epub 2010 Feb 25.Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands.

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