Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID | D0F6NZ | ||||
| Former ID | DIB019438 | ||||
| Drug Name | compound 30 | ||||
| Drug Type | Small molecular drug | ||||
| Formula | C26H29N7O2S | ||||
| InChI | InChI=1S/C26H29N7O2S/c1-6-17(7-2)35-18-10-15(3)23(16(4)11-18)20-12-19(22-14-30-26(36-22)33-25(34)27-5)31-24(32-20)21-13-28-8-9-29-21/h8-14,17H,6-7H2,1-5H3,(H2,27,30,33,34) | ||||
| InChIKey | RYXLLTGGHCFCFK-UHFFFAOYSA-N | ||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | testis-specific kinase 2 | Target Info | Inhibitor | [532008] | |
| LIM domain kinase 1 | Target Info | Inhibitor | [532008] | ||
| LIM domain kinase 2 | Target Info | Inhibitor | [532008] | ||
| testis-specific kinase 1 | Target Info | Inhibitor | [532008] | ||
| References | |||||
| Ref 526087 | Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells. J Biol Chem. 2001 Aug 17;276(33):31449-58. Epub2001 Jun 19. | ||||
| Ref 532008 | Modulation of cofilin phosphorylation by inhibition of the Lim family kinases. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5995-8. | ||||
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