Drug Information

Drug General Information
Drug ID
D0F5NB
Former ID
DIB015704
Drug Name
CD-581
Synonyms
1-(Eicosa-5,8,11-triynoyl)-4-(2-hydroxyethyl)piperazine; 4-(1-Oxo-5,8,11-eicosatriynyl)-1-piprazineethanol
Indication Atopic dermatitis [ICD9: 691.8, 692.9; ICD10:L00-L99] Discontinued in Phase 1 [546435]
CAS Number
CAS 111226-21-2
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [551871]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 546435Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008118)
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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