Drug Information

Drug General Information
Drug ID
D0ER1G
Former ID
DNC012115
Drug Name
4-Hydroxy-piperidine-3-carboxylic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533544]
Formula
C6H11NO3
Canonical SMILES
C1CNCC(C1O)C(=O)O
InChI
1S/C6H11NO3/c8-5-1-2-7-3-4(5)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5+/m0/s1
InChIKey
DAMFVOCECLPLSI-CRCLSJGQSA-N
PubChem Compound ID
21125089
Target and Pathway
Target(s) GABA transporter-3 Target Info Inhibitor [533544]
Sodium- and chloride-dependent GABA transporter 1 Target Info Inhibitor [533544]
KEGG Pathway GABAergic synapse
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
References
Ref 533544J Med Chem. 1982 Oct;25(10):1157-62.Hydroxy- and amino-substituted piperidinecarboxylic acids as gamma-aminobutyric acid agonists and uptake inhibitors.
Ref 533544J Med Chem. 1982 Oct;25(10):1157-62.Hydroxy- and amino-substituted piperidinecarboxylic acids as gamma-aminobutyric acid agonists and uptake inhibitors.

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