Drug Information

Drug General Information
Drug ID
D0EG1F
Former ID
DIB008799
Drug Name
GR-199114X
Drug Type
Small molecular drug
Indication Stomach ulcer [ICD10:K25-K27] Terminated [546618]
Company
Glaxo Wellcome plc
Formula
C28H32FN5O4
Canonical SMILES
N1(C(=O)[C@@H](C(=O)N(c2c1cccc2)C1CCCCC1)NC(=O)Nc1ccc(F<br />)cc1)CC(=O)N1CCCC1
CAS Number
CAS 162271-54-7
PubChem Compound ID
9914672
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info Modulator [546619]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 546618Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009210)
Ref 546619Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009210)

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