Drug Information

Drug General Information
Drug ID
D0E8ZY
Former ID
DIB007692
Drug Name
Vapitadine
Synonyms
Hivenyl; Vapitadine dihydrochloride; R-129160; Vapitadine (oral), Barrier Therapeutics
Drug Type
Small molecular drug
Indication Allergic skin disorders [ICD10:L00-L99] Phase 2 [547977]
Company
Barrier Therapeutics Inc
Formula
C17H20N4O
Canonical SMILES
c12n(c(cn1)C(=O)N)CCc1c(C32CCNCC3)cccc1
PubChem Compound ID
9842252
Target and Pathway
Target(s) Histamine H1 receptor Target Info Antagonist [547978]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 547977Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020866)
Ref 547978Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020866)

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