Drug Information

Drug General Information
Drug ID
D0E8LT
Former ID
DIB006921
Drug Name
Prifinium
Drug Type
Small molecular drug
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Approved [551871]
Formula
C22H28N+
Canonical SMILES
CC[N+]1(CC)CCC(=C(c2ccccc2)c3ccccc3)C1C
InChI
1S/C22H28N/c1-4-23(5-2)17-16-21(18(23)3)22(19-12-8-6-9-13-19)20-14-10-7-11-15-20/h6-15,18H,4-5,16-17H2,1-3H3/q+1
InChIKey
ZYEPZINLLPPBMI-UHFFFAOYSA-N
PubChem Compound ID
4905
Target and Pathway
Target(s) Acetylcholine receptor Target Info Modulator [533658], [551871]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Muscarinic acetylcholine receptors
Acetylcholine regulates insulin secretion
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 533658Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells. J Pharmacol Exp Ther. 1995 Jul;274(1):378-84.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.