TTD | Drug: D0D1GV

Drug General Information
Drug ID	D0D1GV
Former ID	DIB003285
Drug Name	CNS-1237
Indication	Cerebrovascular ischaemia [ICD9: 434.91; ICD10:I61-I63]		Terminated	[545045]
Company	CeNeS Pharmaceuticals Inc
Canonical SMILES	C(=N)(Nc1c2c(c(cc1)OC)cccc2)Nc1c2c3c(C=Cc3ccc2)cc1
CAS Number	CAS 174232-22-5
Target and Pathway
Target(s)	Maxi K potassium channel	Target Info	Modulator	[534454]
KEGG Pathway	cGMP-PKG signaling pathway
	Vascular smooth muscle contraction
	Insulin secretion
	Salivary secretion
	Pancreatic secretion
Reactome	cGMP effects
WikiPathways	Potassium Channels
WikiPathways	Platelet homeostasis
References
Ref 545045	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001959)
Ref 534454	Effects of Ca2+ and Na+ channel inhibitors in vitro and in global cerebral ischaemia in vivo. Eur J Pharmacol. 1997 Aug 6;332(2):121-31.

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Drug Information