Drug Information

Drug General Information
Drug ID
D0CA3J
Former ID
DNCL001786
Drug Name
GSK568859
Indication Atherosclerosis [ICD9: 414.0, 440; ICD10:I70] Discontinued in Phase 1 [548491]
Company
GlaxoSmithKline
Target and Pathway
Target(s) Lipoprotein-associated phospholipase A2 Target Info Modulator [543419]
KEGG Pathway Ether lipid metabolism
Metabolic pathways
Biosynthesis of antibiotics
Pathway Interaction Database Lissencephaly gene (LIS1) in neuronal migration and development
WikiPathways IL1 and megakaryotyces in obesity
Synthesis, Secretion, and Deacylation of Ghrelin
References
Ref 548491Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025982)
Ref 543419(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1432).

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