TTD | Drug: D0A8ZM

Drug General Information
Drug ID	D0A8ZM
Former ID	DNC001253
Drug Name	S-(2-boronoethyl)-L-cysteine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540728]
Formula	C5H12BNO4S
InChI	InChI=1S/C5H12BNO4S/c7-4(5(8)9)3-12-2-1-6(10)11/h4,10-11H,1-3,7H2,(H,8,9)/t4-/m0/s1
InChIKey	OTJHLDXXJHAZTN-BYPYZUCNSA-N
PubChem Compound ID	9877608
PubChem Substance ID	14843352, 24165734, 45624567, 53228269, 92741864, 132566850, 135694770, 136036906, 136368258, 137019918, 160966824, 162629915, 178101948, 226762271, 252457279, 252466839
Target and Pathway
Target(s)	Arginase II, mitochondrial	Target Info	Inhibitor	[535130]
KEGG Pathway	Arginine and proline metabolism
	Metabolic pathways
	Biosynthesis of antibiotics
	Biosynthesis of amino acids
	Amoebiasis
NetPath Pathway	TCR Signaling Pathway
WikiPathways	Urea cycle and metabolism of amino groups
WikiPathways	Metabolism of amino acids and derivatives
References
Ref 540728	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5264).
Ref 535130	Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry. 2001 Mar 6;40(9):2678-88.

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Drug Information