Drug Information

Drug General Information
Drug ID
D09SCI
Former ID
DIB011195
Drug Name
SKF-104351
Drug Type
Small molecular drug
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Terminated [544770]
Company
SmithKline Beecham plc
Formula
C17H14FN3
Canonical SMILES
c1(nc2n(c1c1ccncc1)CCC2)c1ccc(cc1)F
CAS Number
CAS 111908-94-2
PubChem Compound ID
122656
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Modulator [550942]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 544770Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000933)
Ref 550942WO patent application no. 2006,1317,37, Method and composition for treating inflammatory disorders.

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