Drug Information

Drug General Information
Drug ID
D09ROG
Former ID
DNC009091
Drug Name
UCL-2138
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538772]
Formula
C15H20N2O
InChI
InChI=1S/C15H20N2O/c16-13-14-5-7-15(8-6-14)18-12-4-11-17-9-2-1-3-10-17/h5-8H,1-4,9-12H2
InChIKey
RHMNKKOAWUCDRK-UHFFFAOYSA-N
PubChem Compound ID
2994072
PubChem Substance ID
7340828, 10030917, 14847556, 34660349, 48253940, 48329037, 77004567, 85225741, 103361365, 104023960, 111592614, 129130079, 134346296, 135649791, 137014321, 141397265, 143179198, 145752145, 162400864, 162416673, 169436088, 226807395
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [530019]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 538772(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1257).
Ref 530019Bioorg Med Chem Lett. 2009 Apr 15;19(8):2172-5. Epub 2009 Mar 3.Fluorinated non-imidazole histamine H3 receptor antagonists.

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