Drug Information

Drug General Information
Drug ID
D09PGL
Former ID
DAP001049
Drug Name
Capromab
Synonyms
Prostascint (TN)
Drug Type
Antibody
Indication Prostate cancer diagnosis [ICD9: 140-229, 185; ICD10:C61] Approved [538379], [541934], [551871]
Therapeutic Class
Imaging Agents
CAS Number
CAS 145464-28-4
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info [536323]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 538379FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (BLA) 103608.
Ref 541934(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6878).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 536323Synergistic value of single-photon emission computed tomography/computed tomography fusion to radioimmunoscintigraphic imaging of prostate cancer. Semin Nucl Med. 2007 Jan;37(1):17-28.

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